RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-455
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
PCR; dual-luciferase reporter assay etc.
Target
CTGF
Pathway
NA
PubMed ID
Title
Long Noncoding RNA H19 Acts as a Competing Endogenous RNA to Mediate CTGF Expression by Sponging miR-455 in Cardiac Fibrosis
Year
2017
Function
"H19 knockdown could enhance the antifibrotic role of miR-455 and attenuate the CTGF expression and further decrease fibrosis-associated protein synthesis (collagen i, iii, and a-SMA)."